137
Participants
Start Date
December 7, 2020
Primary Completion Date
May 27, 2023
Study Completion Date
May 27, 2023
Insulin glargine
Insulin glargine doses will be determined by calculating the total daily dose (TDD) of insulin and providing 50% of the TDD as follows: start at 0.5 units/kg/day and subtract 0.1 unit/kg/day for 70+ yrs of age, renal insufficiency, pancreatic deficiency and add 0.1 unit/kg/day if hemoglobin A1c in \>10%
NovoLog
Novolog will be administered with each meal if premeal glucose is ≥ 150 mg/dL and at bedtime if glucose is ≥ 200 mg/dL by calculating an individualized insulin sensitivity factor for each subject per the following formula: 1500/total daily dose of insulin = sensitivity factor.
Insulin Fiasp
Fiasp will be administered with each meal if premeal glucose is ≥ 150 mg/dL and at bedtime if glucose is ≥ 200 mg/dL by calculating an individualized insulin sensitivity factor for each subject per the following formula: 1500/total daily dose of insulin = sensitivity factor.
Standard carbohydrate diet
Standard carbohydrate diet as per usual hospital care (75g with each meal)
Boston Medical Center, Boston
Lead Sponsor
Collaborators (1)
Novo Nordisk A/S
INDUSTRY
Boston Medical Center
OTHER