40
Participants
Start Date
August 26, 2020
Primary Completion Date
February 16, 2022
Study Completion Date
December 1, 2025
Zanubrutinib, Lenalidomide and Rituximab (ZR2)
"Induction therapy:~The ZR2 regimen will be given from day 1 of each cycle of treatment. Each cycle will last for 21 days. Participants will receive a total of 6 cycles.~Dosage:~1. Zanubrutinib, 160 mg bid, po, day 1-21;~2. Lenalidomide, 25 mg qd, po, day 2-11;~3. Rituximab, 375 mg/m2, ivgtt, day 1.~Maintenance therapy:~Patients who receive complete response or partial response after induction therapy will receive lenalidomide 25 mg qd po during 1-10 days in every 21 days, for a maximum of 2 years."
Shanghai Ruijin Hospital, Shanghai
Ruijin Hospital
OTHER