Development and Validation of a Model to Predict Fast Progression in Glaucoma

TerminatedOBSERVATIONAL
Enrollment

1,152

Participants

Timeline

Start Date

July 20, 2021

Primary Completion Date

April 24, 2023

Study Completion Date

April 24, 2023

Conditions
GlaucomaPrimary Open Angle GlaucomaGlaucoma, Suspect
Interventions
DIAGNOSTIC_TEST

Collection of genetic material

Blood samples will be processed for extraction of DNA and genotyping. 10 ml of blood will be collected using standard procedures. The samples will be de-identified and receive a masked ID which will correspond to the existing masked ID in the DGR database. 2 ml will be sent to Genentech using frozen samples for genotyping using the Illumina Global Screening Array (GSA) kit. The remaining will be processed and stored at the Duke Eye Center. These samples may be maintained indefinitely or until they are exhausted. These samples will not be available for diagnostic or therapeutic purposes.

Trial Locations (1)

27705

Duke University Eye Center, Durham

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

lead

Duke University

OTHER