A Study of Dabrafenib in Combination With Trametinib in Chinese Patients With BRAF V600E Mutant Metastatic NSCLC

PHASE2CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

August 19, 2020

Primary Completion Date

November 7, 2024

Study Completion Date

November 7, 2024

Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG

Dabrafenib

Dabrafenib will be provided by the sponsor to the investigative site or supplied locally as commercially available. Dabrafenib will be administered orally twice daily (150 mg BID) for Days 1-21 of a 21-day cycle.

DRUG

Trametinib

Trametinib will be provided by the sponsor to the investigative site or supplied locally as commercially available. Trametinib will be administered orally once daily (2 mg QD) for Days 1-21 of a 21-day cycle

Trial Locations (8)

100036

Novartis Investigative Site, Beijing

150081

Novartis Investigative Site, Harbin

200032

Novartis Investigative Site, Shanghai

310003

Novartis Investigative Site, Hangzhou

310022

Novartis Investigative Site, Hangzhou

410013

Novartis Investigative Site, Changsha

510060

Novartis Investigative Site, Guangzhou

610041

Novartis Investigative Site, Chengdu

Sponsors
All Listed Sponsors
lead

Novartis Pharmaceuticals

INDUSTRY