A Study to Compare Efficacy and Safety of Trifarotene Cream When Used With an Oral Antibiotic for the Treatment of Severe Acne Vulgaris (AV)

PHASE4CompletedINTERVENTIONAL
Enrollment

202

Participants

Timeline

Start Date

July 29, 2020

Primary Completion Date

April 26, 2021

Study Completion Date

April 26, 2021

Conditions
Acne Vulgaris
Interventions
DRUG

Trifarotene cream

Trifarotene 50 mcg/g cream applied topically once daily on face for 12 weeks.

DRUG

Doxycycline hyclate

Doxycycline hyclate delayed release 120 mg tablets was administered orally for 12 weeks.

DRUG

Trifarotene Vehicle

Trifarotene 50 mcg/g vehicle cream was applied topically once daily on face for 12 weeks.

DRUG

Doxycycline Placebo

Doxycycline hyclate delayed release 120 mg placebo tablets was administered orally for 12 weeks.

Trial Locations (26)

705

Galderma Investigational Site, Aibonito

11790

Galderma Investigational Site, Stony Brook

18249

Galderma Investigational Site, Sugarloaf

20850

Galderma Investigational Site, Rockville

27262

Galderma Investigational Site, High Point

30263

Galderma Investigational Site, Newnan

33027

Galderma Investigational Site, Miramar

33180

Galderma Investigational Site, Aventura

33486

Galderma Investigational Site, Boca Raton

37922

Galderma Investigational Site, Knoxville

47150

Galderma Investigational Site, New Albany

47715

Galderma Investigational Site, Evansville

48088

Galderma Investigational Site, Warren

55112

Galderma Investigational Site, New Brighton

71913

Galderma Investigational Site, Hot Springs

Galderma Investigational Site, Charleston

72758

Galderma Investigational Site, Rogers

72916

Galderma Investigational Site, Fort Smith

75246

Galderma Investigational Site, Dallas

76011

Galderma Investigational Site, Arlington

76051

Galderma Investigational Site, Grapevine

78218

Galderma Investigational Site, San Antonio

78249

Galderma Investigational Site, San Antonio

78660

Galderma Investigational Site, Pflugerville

89148

Galderma Investigational Site, Las Vegas

92663

Galderma Investigational Site, Newport Beach

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Galderma R&D

INDUSTRY

NCT04451330 - A Study to Compare Efficacy and Safety of Trifarotene Cream When Used With an Oral Antibiotic for the Treatment of Severe Acne Vulgaris (AV) | Biotech Hunter | Biotech Hunter