508
Participants
Start Date
August 18, 2020
Primary Completion Date
August 31, 2026
Study Completion Date
August 31, 2028
reduced dosage IMRT
"1. Gemcitabine plus cisplatin induction chemotherapy: gemcitabine is injected intravenously at the dose of 1000 mg/m2 on the 1st and 8th day (within 30 minutes) for 3 cycles; cisplatin is injected intravenously at the dose of 80 mg/m2 on the 1st day, for 3 cycles. 1 cycles per 3 weeks.~2. Concurrent cisplatin chemotherapy: cisplatin is given at a dose of 100 mg/m2 via a continuous intravenous infusion during radiotherapy and starts on the 1st day of radiotherapy for 2 cycles. 1 cycles per 3 weeks.~3. IMRT: PTVnx:63.6Gy/30Fr/2.12Gy; PTVnd:63.6Gy/30Fr/2.12Gy; PTV1:54Gy/30Fr/1.8Gy; PTV2:49.2Gy/30Fr/1.64Gy"
conventional dosage IMRT
"1. Gemcitabine plus cisplatin induction chemotherapy: gemcitabine is injected intravenously at the dose of 1000 mg/m2 on the 1st and 8th day (within 30 minutes) for 3 cycles; cisplatin is injected intravenously at the dose of 80 mg/m2 on the 1st day, for 3 cycles. 1 cycles per 3 weeks.~2. Concurrent cisplatin chemotherapy: cisplatin is given at a dose of 100 mg/m2 via a continuous intravenous infusion during radiotherapy and starts on the 1st day of radiotherapy for 2 cycles. 1 cycles per 3 weeks.~3. IMRT: PTVnx:69.96Gy/33Fr/2.12Gy; PTVnd:69.96Gy/33Fr/2.12Gy; PTV1:59.4Gy/33Fr/1.8Gy; PTV2:54Gy/33Fr/1.64Gy"
NOT_YET_RECRUITING
National Cancer Centre Singapore, Singapore
RECRUITING
Sun Yat-sen University Cancer Center, Guangzhou
NOT_YET_RECRUITING
Cancer Center of Guangzhou Medical University, Guangzhou
NOT_YET_RECRUITING
Yuebei People's Hospital, Shaoguan
RECRUITING
Zhongshan People's Hospital, Zhongshan
NOT_YET_RECRUITING
Wuzhou Red Cross Hospital, Wuzhou
National Cancer Centre, Singapore
OTHER
Affiliated Cancer Hospital & Institute of Guangzhou Medical University
OTHER
Zhongshan People's Hospital, Guangdong, China
OTHER
Yuebei People's Hospital
OTHER
Wuzhou Red Cross Hospital
OTHER
Sun Yat-sen University
OTHER