An Open-Label Study of INV-1120 As a Single Agent and in Combination with Pembrolizumab in Adult Patients with Advanced Solid Tumors

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

78

Participants

Timeline

Start Date

June 26, 2020

Primary Completion Date

March 31, 2026

Study Completion Date

December 31, 2026

Conditions
CancerSolid Tumor, AdultCancer MetastaticSolid CarcinomaSolid Tumor, Unspecified, AdultTumor, Solid
Interventions
DRUG

INV-1120

INV-1120 is an investigational selective and potent small molecule indicated for the treatment of solid malignancies including, but not limited to colorectal, breast, pancreatic, lung and liver cancers.

COMBINATION_PRODUCT

Pembrolizumab

Pembrolizumab will be administered as a dose of 200 mg on Day 1 of each 3-week treatment cycle.

Trial Locations (3)

47905

Horizon Oncology Research, LLC,, Lafayette

78229

START, San Antonio

UT Health, San Antonio

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

Shenzhen Ionova Life Sciences Co., Ltd.

INDUSTRY