Oral EPI-7386 in Patients with Castration-Resistant Prostate Cancer

PHASE1TerminatedINTERVENTIONAL
Enrollment

71

Participants

Timeline

Start Date

June 23, 2020

Primary Completion Date

October 31, 2024

Study Completion Date

December 3, 2024

Conditions
Prostate Cancer
Interventions
DRUG

EPI-7386 (QD)

Once daily oral dose of EPI-7386

DRUG

EPI-7386 (BID)

Twice daily oral dose of EPI-7386

DRUG

Abiraterone acetate

Once daily dose of abiraterone acetate

DRUG

Apalutamide

Once daily dose of apalutamide

Trial Locations (9)

10065

Memorial Sloan Kettering Cancer Center, New York

14203

Great Lakes Cancer Center, Buffalo

30322

Winship Cancer Institute of Emory University, Atlanta

34952

Hematology Oncology Associates of the Treasure Coast, Port Saint Lucie

63110

Washington University School of Medicine in St. Louis, St Louis

89169

Comprehensive Cancer Center of NV Las Vegas, Las Vegas

02215

Massachusetts General Hospital, Boston

V5Z 4E6

BC Cancer, Vancouver

H2X0A9

Centre hospitalier de l'Université de Montréal, Montreal

Sponsors
All Listed Sponsors
lead

ESSA Pharmaceuticals

INDUSTRY

NCT04421222 - Oral EPI-7386 in Patients with Castration-Resistant Prostate Cancer | Biotech Hunter | Biotech Hunter