226
Participants
Start Date
August 14, 2023
Primary Completion Date
September 30, 2027
Study Completion Date
September 30, 2027
Methylphenidate
10mg twice per day, at 8am and 12pm, for one week, then increased to 20mg twice daily, at 8am and 12pm, for the next 7 weeks during the double-blinded period.
Placebo
When assigned to receive the placebo during the double-blinded period, subjects will be given a sugar pill for 8 weeks. The sugar pill will be taken twice per day, at 8am and 12pm.
Methylphenidate
During the open-label extension phase, dosing will begin at 10mg twice per day, at 8am and 12pm, for one week. The dosage will then increase to 20mg twice daily, at 8am and 12pm, for the next 7 weeks.
RECRUITING
Miami VA Healthcare System, Miami, FL, Miami
RECRUITING
VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
RECRUITING
VA NY Harbor Healthcare System, New York, NY, New York
RECRUITING
VA Portland Health Care System, Portland, OR, Portland
VA New York Harbor Healthcare System
FED
Portland VA Medical Center
FED
Miami VA Healthcare System
FED
VA Boston Healthcare System
FED
VA Office of Research and Development
FED