Low-dose S-ketamine in Women With Prenatal Depression

NACompletedINTERVENTIONAL
Enrollment

364

Participants

Timeline

Start Date

June 19, 2020

Primary Completion Date

August 3, 2022

Study Completion Date

August 3, 2022

Conditions
Prenatal DepressionKetaminePostpartum Depression
Interventions
DRUG

S-ketamine

For women in this group, active drug (s-ketamine 0.2 mg/kg in 20 ml normal saline) will be infused at a rate of 30 ml/h (infusion finished in 40 minutes) after giving birth. They will be monitored for 60 minutes and then sent back to the ward.

DRUG

Placebo

For women in this group, placebo (20 ml normal saline) will be infused at a rate of 30 ml/h (infusion finished in 40 minutes) after giving birth. They will be monitored for 60 minutes and then sent back to the ward.

Trial Locations (7)

100034

Peking University First Hospital, Beijing

Unknown

Beijing Tiantan Hospital, Beijing

Peking University International Hospital, Beijing

Hunan Provincial Maternal and Child Health Care Hospital, Changsha

Huaian Maternal and Child Health Care Hospital, Huaian

Nanjing Maternal and Child Health Care Hospital, Nanjing

Women's Hospital School Of Medicine Zhejiang University, Hangzhou

Sponsors
All Listed Sponsors
collaborator

Peking University International Hospital

OTHER

collaborator

Hunan Provincial Maternal and Child Health Care Hospital

OTHER

collaborator

Nanjing Medical University

OTHER

collaborator

Women's Hospital School Of Medicine Zhejiang University

OTHER

lead

Peking University First Hospital

OTHER