36
Participants
Start Date
July 1, 2020
Primary Completion Date
December 31, 2026
Study Completion Date
December 31, 2027
[18F]-GE-180 PET
serial \[18F\]-GE-180 PET imaging to assess microglia activation
3T MRI
serial MR imaging (i) to determine infarct characteristics, (ii) to identify gray and white matter structures connected to the infarct, (iii) to detect incident lesions, and (iv) to quantify longitudinal changes e.g. of cortical thickness
immune cell profiling in blood
Cell-specific cytokine profiles, markers of activation, terminal differentiation as well as cytotoxicity will be assesses using flow cytometry.
RECRUITING
Insitute for Stroke and Dementia Research, Munich
RECRUITING
Department of Nuclear Medicine, Munich
Universitätsklinikum Hamburg-Eppendorf
OTHER
University Hospital Muenster
OTHER
Martin Dichgans
OTHER