Inflammatory faCtors AfteR acUte Ischemic Stroke

NARecruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

July 1, 2020

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2027

Conditions
Ischemic Stroke
Interventions
DIAGNOSTIC_TEST

[18F]-GE-180 PET

serial \[18F\]-GE-180 PET imaging to assess microglia activation

DIAGNOSTIC_TEST

3T MRI

serial MR imaging (i) to determine infarct characteristics, (ii) to identify gray and white matter structures connected to the infarct, (iii) to detect incident lesions, and (iv) to quantify longitudinal changes e.g. of cortical thickness

DIAGNOSTIC_TEST

immune cell profiling in blood

Cell-specific cytokine profiles, markers of activation, terminal differentiation as well as cytotoxicity will be assesses using flow cytometry.

Trial Locations (2)

81377

RECRUITING

Insitute for Stroke and Dementia Research, Munich

RECRUITING

Department of Nuclear Medicine, Munich

All Listed Sponsors
collaborator

Universitätsklinikum Hamburg-Eppendorf

OTHER

collaborator

University Hospital Muenster

OTHER

lead

Martin Dichgans

OTHER