SPEARHEAD 2 Study in Subjects With Recurrent or Metastatic Head and Neck Cancer

PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

July 2, 2020

Primary Completion Date

December 31, 2021

Study Completion Date

December 31, 2021

Conditions
Head and Neck Cancer
Interventions
GENETIC

ADP-A2M4 in combination with pembrolizumab.

Single infusion of autologous genetically modified ADP-A2M4 Dose: 1.0 x109 to 10x109 transduced cells by a single intravenous infusion Repeat doses of pembrolizumab every 3 weeks. Dose: 200mg

Trial Locations (8)

26506

West Virginia University Cancer Institute, Morgantown

37212

Vanderbilt-Ingram Cancer Center, Nashville

48201

Karmanos Cancer Insitute, Detroit

66160

University of Kansas Medical Center, Kansas City

77030

MD Anderson Cancer Center, Houston

85054

Mayo Clinic Phoenix, Phoenix

92093

University of California San Diego, San Diego

97213

Providence Cancer Institute Franz Head and Neck Clinic, Portland

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Adaptimmune

INDUSTRY

NCT04408898 - SPEARHEAD 2 Study in Subjects With Recurrent or Metastatic Head and Neck Cancer | Biotech Hunter | Biotech Hunter