4
Participants
Start Date
November 4, 2020
Primary Completion Date
October 12, 2021
Study Completion Date
October 12, 2021
Dose Finding Phase (MTD)
Enrollment to the dose escalation phase will be staggered. The first patient enrolled on each of the 3 dose levels (DL1, DL2 and DL3) will have to complete the 14-day toxicity monitoring window prior to enrollment of the next patients. Prior to dose escalation, all patients at a particular dose level should have completed the minimum 14-day toxicity monitoring window before enrolling to a higher dose level.
Partially HLA-matched SARS-CoVSTs
Infusion of SARS-CoVSTs at the MTD level as determined in the Dose Finding Phase
Routine care (no SARS-CoVSTs)
Patients receive routine care for COVID19 per institutional standards (including antivirals such as remdesivir or other FDA-EUA approved products and thromboprophylaxis).
Houston Methodist Hospital, Houston
Collaborators (1)
Center for Cell and Gene Therapy, Baylor College of Medicine
OTHER
AlloVir
INDUSTRY
The Methodist Hospital Research Institute
OTHER
Baylor College of Medicine
OTHER