NCT04398524 - A Phase II Study of Cemiplimab and ISA101b in Patients With Recurrent/Metastatic HPV16 Positive OPC | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

July 1, 2021

Primary Completion Date

June 30, 2024

Study Completion Date

December 30, 2024

Conditions

Squamous Cell Carcinoma of the Oropharynx

Interventions

DRUG

ISA101b

ISA101b 4 times plus cemiplimab every 3 weeks for up to 24 months

Trial Locations (41)

4000

Centre Hospitalier Universitaire de Liege, Liège

10060

Institute of Cancer Research and Treatment of Candiolo, Turin

14263

Roswell Park Cancer Institute, Buffalo

28027

University Clinic of Navarra - Madrid, Madrid

31008

University Clinic of Navarra, Pamplona

33000

Saint Andre Hospital, Department of Oncology, Bordeaux

33612

H. Lee Moffitt Cancer Center & Research Institute, Tampa

50937

University Hospital Cologne, Department of Otorhinolaryngology (ENT), Cologne

63110

Washington University, St Louis

69008

Leon Berard Center, Department of Medical Oncology, Lyon

80045

Anschutz Cancer Pavilion, Aurora

91010

City of Hope National Medical Center, Duarte

94115

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco

97213

Providence Portland Medical Center, Portland

02114

Massachusetts General Hospital, Boston

Unknown

University Hospital Antwerp, Antwerp

University Hospital Ghent, Ghent

Clinic of Oncology, Olomouc

Institute of Radiation Oncology, Prague

University Hospital Motol, Clinic of Oncology, Prague

CHU La Timone - La Timone Children's Hospital, Marseille

Georges Pompidou European Hospital, Paris

Jean Godinot Institute, Cancer Research Center, Reims

Paul Strauss Center, Strasbourg

Gustave Roussy Institute, Villejuif

University Hospital Giessen and Marburg GmbH, Giessen

University Hospital Mannheim, Mannheim

Caritas Klinikum, Saarbrücken

University Hospital Ulm, Ulm

Hadassah Medical Center, Jerusalem

The Tel Aviv Sourasky Medical Cente, Tel Aviv

Università degli Studi di Brescia, Brescia

European Institute of Oncology (IEO), IRCCS, Department of Otolaryngology and Facial Cervix Surgery, Milan

Fondazione IRCCS Istituto Nazionale dei Tumori, Milan

National Cancer Institute - IRCCS, Naples

Hospital Clinic of Barcelona, Barcelona

University Hospital Vall d'Hebron, Barcelona

Guy's Hospital, London

Royal Marsden Hospital, London

Royal Marsden Hospital - Sutton, Sutton

08908

Catalan Institute of Oncology, Hospital Duran i Reynals, Department of Oncology, L'Hospitalet de Llobregat