Evaluate the Safety and Clinical Activity of HH2853

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

254

Participants

Timeline

Start Date

September 8, 2020

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
FL LymphomaEpithelioid SarcomaPeripheral T Cell LymphomaAdvanced Solid Tumor
Interventions
DRUG

HH2853 Tablets

Proposed daily dose (BID): 50mg, 100mg, 200mg, 400mg, 600mg, 800mg, 1000mg. It is possible for additional and/or intermediate dose levels to be added during the course of the study. Cohorts may be added at any dose level below the MTD in order to better understand safety, PK or PD.

Trial Locations (25)

32224

COMPLETED

Mayo Clinic, Jacksonville

55905

COMPLETED

Mayo Clinic, Rochester

78240

COMPLETED

NEXT Oncology, San Antonio

85054

COMPLETED

Mayo Clinic, Phoenix

100142

RECRUITING

Beijing Cancer Hospital, Beijing

Unknown

RECRUITING

The First Affiliated Hospital of Anhui Medical University, Hefei

RECRUITING

Beijing Cancer Hospital, Beijing

RECRUITING

Beijing Jishuitan Hospital, Beijing

RECRUITING

Sun Yat-Sen University Cancer Hospital, Guangzhou

RECRUITING

Affiliated Tumor Hospital of Guangxi Medical University, Nanning

RECRUITING

Henan Cancer Hospital, Zhengzhou

RECRUITING

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

RECRUITING

Hunan Cancer Hospital, Changsha

RECRUITING

Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing

RECRUITING

Liaoning Cancer Hospital&Institute, Shenyang

RECRUITING

Shengjing Hospital Of China Medical University, Shenyang

RECRUITING

Linyi Tumor Hospital, Linyi

RECRUITING

Shanghai Sixth People's Hospital, Shanghai

RECRUITING

Zhongshan Hospital Fudan University, Shanghai

RECRUITING

Shanxi Cancer Hospital, Taiyuan

RECRUITING

West China Hospital of Sichuan University, Chengdu

RECRUITING

Tianjin Cancer Hospital, Tianjin

RECRUITING

Zhejiang Cancer Hospital, Hangzhou

RECRUITING

Beijing Cancer Hospital, Beijing

RECRUITING

Sun Yat-Sen University Cancer Hospital, Guangzhou

Sponsors
All Listed Sponsors
lead

Haihe Biopharma Co., Ltd.

INDUSTRY