28
Participants
Start Date
December 29, 2020
Primary Completion Date
August 31, 2026
Study Completion Date
August 31, 2027
Vincristine
IV push over 1 minute with dosing ranging from 0.24mg up to 1.5mg
Cyclophosphamide
IV over 60 minutes with dosing ranging from 220mg to 1200mg
Vinorelbine
IV push over 6-10 minutes with dosing ranging from 4mg-25mg
Actinomycin D
Actinomycin D should not be given with radiation. Will be administered through IV over 3-5 minutes with dosing ranging from 0.025mg-0.045mg
Cyclophosphamide Pill
Based on Body Surface Area (BSA) round to nearest 25mg
RECRUITING
Montefiore Medical Cancer Center, The Bronx
RECRUITING
Roswell Park Comprehensive Cancer Center, Buffalo
RECRUITING
University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill
RECRUITING
Duke Children's Hospital, Durham
RECRUITING
Carolinas Medical Center, Levine Cancer Institute, Charlotte
RECRUITING
University of Florida, Gainesville
RECRUITING
University of Miami - Sylvester Comprehensive Cancer Center, Miami
RECRUITING
Moffitt Cancer Center, Tampa
RECRUITING
Johns Hopkins All Children's Hospital, St. Petersburg
RECRUITING
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham
RECRUITING
Vanderbilt - Ingram Cancer Center, Nashville
RECRUITING
Nationwide Children's Hospital, Columbus
RECRUITING
Cleveland Clinic, Cleveland
RECRUITING
University of Texas Southwestern Medical Center, Dallas
RECRUITING
MD Anderson, Houston
RECRUITING
Children's Hospital of Colorado, Aurora
RECRUITING
Primary Children's Medical Center/Utah, Salt Lake City
RECRUITING
Connecticut Children's Medical Center, Hartford
National Pediatric Cancer Foundation
OTHER
H. Lee Moffitt Cancer Center and Research Institute
OTHER