Effect of GOCOVRI (Amantadine, Extended Release Capsules) on Gait in Parkinson's Disease

PHASE4CompletedINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

November 5, 2020

Primary Completion Date

September 1, 2022

Study Completion Date

September 30, 2022

Conditions
Parkinson Disease
Interventions
DRUG

GOCOVRI

"Participants will have gait and balance baseline assessment and then repeat assessment after being on full-dose of GOCOVRI for two weeks. The assessments will include measures of gait, balance and dyskinesia. Participants will also wear body-worn sensors (on wrist, feet and lumbar area) during daily-life for seven days to quantify mobility.~GOCOVRI will be started at 137mg/day for two weeks and then increased to 274mg/day for two weeks. Participants will repeat baseline assessments and then decrease to a dose of 137mg/day of GOCOVRI for one week, before stopping the medication completely.~All participants will receive GOCOVRI and they will know that they are on study drug. No placebo group."

Trial Locations (1)

97239

Oregon Health & Science University, Portland

Sponsors
All Listed Sponsors
collaborator

Adamas Pharmaceuticals, Inc.

INDUSTRY

lead

Oregon Health and Science University

OTHER

NCT04387773 - Effect of GOCOVRI (Amantadine, Extended Release Capsules) on Gait in Parkinson's Disease | Biotech Hunter | Biotech Hunter