Optimization of NIBS for Treatment of Addiction

NARecruitingINTERVENTIONAL
Enrollment

126

Participants

Timeline

Start Date

April 4, 2021

Primary Completion Date

October 31, 2027

Study Completion Date

October 31, 2027

Conditions
Opioid-use DisorderChronic Pain
Interventions
DEVICE

Active Comparator: Active tDCS + Active TUS

"Device: Active comparator device: Active transcranial Direct Current Stimulation (tDCS). Subjects will receive 20 minutes of active tDCS. During each Active stimulation session, stimulation will be applied for the full 20 minutes.~Device: Active comparator device: Active Transcranial Ultrasound (TUS). Subjects will receive 20 minutes of active Transcranial Ultrasound (TUS). During active stimulation the (TUS) will be active for the full 20 minutes."

DEVICE

Sham Comparator: Sham tDCS + Sham TUS

"Device: SHAM Comparator Device: transcranial Direct Current Stimulation (tDCS) Subjects will receive 20 minutes of sham tDCS. In the sham group, the tDCS device will not be active for the full 20 minutes.~Device: Transcranial Ultrasound (TUS) Subjects will receive 20 minutes of sham TUS. During sham stimulation the ultrasound will not be active for the full 20 minutes."

Trial Locations (2)

60612

RECRUITING

University of Illinois Health/ University of Illinois at Chicago, Hinsdale

44106-1716

RECRUITING

University Hospitals Cleveland Medical Center/ Dahms Clinical Research Unit, Cleveland

All Listed Sponsors
collaborator

Highland Instruments, Inc.

INDUSTRY

lead

Case Western Reserve University

OTHER