Prospective Study to Assess Disease Activity and Biomarkers in Minority Participants With Relapsing Multiple Sclerosis (RMS) After Initiation and During Treatment With Ocrelizumab

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

179

Participants

Timeline

Start Date

July 30, 2020

Primary Completion Date

December 29, 2025

Study Completion Date

December 29, 2025

Conditions
Multiple Sclerosis, Relapsing
Interventions
DRUG

Ocrelizumab

Ocrelizumab will be administered intravenously (IV) at a dose of 600 mg every 24 weeks. The first dose of ocrelizumab will be administered as two 300 mg IV infusions given 14 days apart. For the subsequent dose, ocrelizumab will be administered as a single 600 mg IV infusion every 24 weeks.

Trial Locations (32)

969

Centro Internacional De Mercadeo, Guaynabo

10065

Weill Cornell Medical College, New York

13210

SUNY Upstate Medical Center, Syracuse

19107

Jefferson University Hospitals, Thomas Jefferson University, Philadelphia

20007

Georgetown University Medical Center, Washington D.C.

21287

Johns Hopkins University Neurology Research Office, Baltimore

23502

Multiple Sclerosis Center of Tidewater, Norfolk

27401

Guilford Neurologic Associates, Greensboro

30309

Shepherd Center Inc., Atlanta

30327

Atlanta Neuroscience Institute, Atlanta

32250

Baptist Neurology - Beaches, Jacksonville Beach

33136

University of Miami Miller School of Medicine, Miami

37232

Vanderbilt University Medical Center, Nashville

38018

Neurology Clinic - Cordova, Cordova

45417

Neurology Specialists, Inc, Dayton

46256

Josephson Wallack Munshower Neurology PC, Indianapolis

48201

Wayne State University, Detroit

53215

Wheaton Franciscan Healthcare - St. Francis Outpatient Center, Milwaukee

53226

Medical College of Wisconsin, Milwaukee

60637

University of Chicago, Chicago

63110

Washington University School of Medicine, St Louis

75034

North Texas Institute of Neurology and Headache NextStage Clinical Research Clinic, Frisco

75390

University of Texas Southwestern Medical Center, Dallas

77030

Baylor College of Medicine Medical Center, Houston

85013

Barrow Neurological Institute, Phoenix

85032

Center for Neurology and Spine - Phoenix - Hunt - PPDS, Phoenix

98122

Swedish Neuroscience Institute, Seattle

90033-5315

Keck School of Medicine of USC, Los Angeles

60612-3244

Rush University Medical Center, Chicago

21201-1642

University of Maryland Medical Center, Baltimore

07601

Hackensack University Medical Center, Hackensack

00100

Aga Khan University Hospital, Nairobi

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Genentech, Inc.

INDUSTRY

NCT04377555 - Prospective Study to Assess Disease Activity and Biomarkers in Minority Participants With Relapsing Multiple Sclerosis (RMS) After Initiation and During Treatment With Ocrelizumab | Biotech Hunter | Biotech Hunter