Tyrosine Hydroxylase Antibody Levels in Autoimmune Polyglandular Syndrome Type 1 Associated Keratitis

NACompletedINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

January 1, 2014

Primary Completion Date

June 6, 2014

Study Completion Date

June 6, 2014

Conditions
Autoimmune Polyglandular Syndrome Type IAutoimmune Keratitis
Interventions
DIAGNOSTIC_TEST

Detection of autoantibodies

Blood was obtained from each patient for testing the endocrine functions and determination of a panel of autoantibodies to the following: Side-chain cleavage enzyme (SSC), Aromatic L-amino acid decarboxylase (AADC), Tryptophan hydroxylase (TPH),Tyrosine hydroxylase ( TH), 17α-hydroxylase (17α-OH), Cytochrome P450 1A2 (CYP1A2), 21-hydroxylase (21-OH), Potassium channel regulatory protein (KCNRG), Tyrosine phosphatase-like protein IA-2 (IA-2), Glutamic acid decarboxylase 65 (GAD65), NACT Leucine-Rich-Repeat-Protein 5 (NALP5), and Interleukin (IL) 22.

All Listed Sponsors
lead

The Eye Center and The Eye Foundation for Research in Ophthalmology

OTHER

NCT04375852 - Tyrosine Hydroxylase Antibody Levels in Autoimmune Polyglandular Syndrome Type 1 Associated Keratitis | Biotech Hunter | Biotech Hunter