342
Participants
Start Date
June 3, 2020
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2025
5-Fluorouracil
Day 1 q2w: 2600 mg/m² IV over 24 hours
Calcium folinate
Day 1 q2w: 200 mg/m² IV over 2 hours
Oxaliplatin
Day 1 q2w: 85 mg/m² IV over 2 hours
Docetaxel
Day 1 q2w: 50 mg/m² IV over 2 hours
Radiation
25 fractions (5 each week over 5 weeks) each 1,8 Gy to a total of 45 Gy
Oxaliplatin during radiotherapy
Day 1, 8, 15, 22, 29: 45 mg/m² IV over 2 hours
5-Fluorouracil during radiotherapy
day 1 - 33: 225 mg/m²/day IV continuously
Unversity Hospital Mannheim, Mannheim
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
OTHER
Deutsche Krebshilfe e.V., Bonn (Germany)
OTHER
Universitätsmedizin Mannheim
OTHER