IO-202 as Monotherapy and IO-202 Plus Azacitidine ± Venetoclax in Patients in AML and CMML

PHASE1CompletedINTERVENTIONAL
Enrollment

67

Participants

Timeline

Start Date

September 14, 2020

Primary Completion Date

January 31, 2025

Study Completion Date

January 31, 2025

Conditions
AML With Monocytic DifferentiationCMML
Interventions
BIOLOGICAL

IO-202

IO-202 as monotherapy

BIOLOGICAL

IO-202 and Azacitidine

IO-202 and azacitidine combination therapy

BIOLOGICAL

IO-202 and Azacitidine + Venetoclax

IO-202 and azacitidine + venetoclax combination therapy

BIOLOGICAL

IO-202 and Azacitidine

IO-202 and azacitidine combination therapy

Trial Locations (14)

10021

Weill Cornell Medical College, New York Presbyterian Hospital (110), New York

30322

Winship Cancer Institute of Emory University (105), Atlanta

44195

Cleveland Clinic, Taussig Cancer Institute (111), Cleveland

60637

The University of Chicago (113), Chicago

75390

University of Texas Southwestern, Simmons Comprehensive Cancer Center (104), Dallas

77030

MD Anderson Cancer Center (101), Houston

80045

University of Colorado, Anschutz Medical Campus (103), Aurora

90095

UCLA, Medical Center Division of Hematology/Oncology (119), Los Angeles

91010

City of Hope (106), Duarte

92868

University of California, Irvine (107), Irvine

94143

University of California, San Francisco (118), San Francisco

94305

Stanford University (114), Palo Alto

95817

University California, Davis (117), Davis

97239

Oregon Health and Science University, Center for Hematologic Malignancies (116), Portland

Sponsors
All Listed Sponsors
collaborator

California Institute for Regenerative Medicine (CIRM)

OTHER

lead

Immune-Onc Therapeutics

INDUSTRY

NCT04372433 - IO-202 as Monotherapy and IO-202 Plus Azacitidine ± Venetoclax in Patients in AML and CMML | Biotech Hunter | Biotech Hunter