MSCs in COVID-19 ARDS

PHASE3TerminatedINTERVENTIONAL
Enrollment

223

Participants

Timeline

Start Date

April 30, 2020

Primary Completion Date

January 14, 2021

Study Completion Date

January 2, 2022

Conditions
Mesenchymal Stromal CellsRemestemcel-LAcute Respiratory Distress SyndromeCOVID
Interventions
BIOLOGICAL

Remestemcel-L

administered twice during the first week, with the second infusion at 4 days following the first injection (± 1 day)

DRUG

Placebo

administered twice during the first week, with second infusion at 4 days following the first injection (± 1 day)

Trial Locations (21)

10016

New York University Langone Health, New York

10029

Mount Sinai Health, New York

10075

Northwell Health, New York

19104

University of Pennsylvania Health System, Philadelphia

21201

University of Maryland, Baltimore

22908

University of Virginia, Charlottesville

27610

WakeMed, Raleigh

27710

Duke University Medical Center, Durham

30308

Emory University, Atlanta

44195

Cleveland Clinic Foundation, Cleveland

46825

Lutheran Hospital, Fort Wayne

48109

University of Michigan, Ann Arbor

70121

Ochsner Clinic, New Orleans

75093

Baylor, Smith & White, Plano

77030

Houston Methodist Hospital, Houston

85297

Dignity Health, Gilbert

90033

University of Southern California, Los Angeles

94305

Stanford University, Stanford

04102

Maine Medical Center, Portland

02115

Brigham and Women's Hospital, Boston

03766

Dartmouth-Hitchcock, Lebanon

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Mesoblast, Inc.

INDUSTRY

collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Icahn School of Medicine at Mount Sinai

OTHER