Pharmacokinetic Study of Cabotegravir and Rilpivirine Long-acting Intramuscular Injections in Healthy Adult Participants

PHASE1CompletedINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

September 16, 2020

Primary Completion Date

December 26, 2021

Study Completion Date

December 26, 2021

Conditions
HIV Infections
Interventions
DRUG

Cabotegravir Tablets

Cabotegravir tablets will be white to almost white oval shaped film coated tablets with a unit dose of 30 mg and will be administered orally.

DRUG

Rilpivirine Tablets

Rilpivirine tablets will be off-white, round, biconvex film coated tablets with a unit dose of 25 mg and will be administered orally.

DRUG

Cabotegravir extended release suspension for injection (long-acting)

Cabotegravir long-acting will be a sterile white to slightly pink suspension containing 200 mg per mL of GSK1265744 as free acid for administration by intramuscular injection.

DRUG

Rilpivirine extended release suspension for injection (long-acting)

Rilpivirine long-acting will be a sterile white suspension containing 300 mg per mL of rilpivirine as the free base for administration by intramuscular injection.

Trial Locations (1)

91206

GSK Investigational Site, Glendale

Sponsors
All Listed Sponsors
collaborator

Janssen Pharmaceuticals

INDUSTRY

collaborator

GlaxoSmithKline

INDUSTRY

lead

ViiV Healthcare

INDUSTRY