Study of Combination Therapy With INCMGA00012 (Anti-PD-1), INCAGN02385 (Anti-LAG-3), and INCAGN02390 (Anti-TIM-3) in Participants With Select Advanced Malignancies

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

61

Participants

Timeline

Start Date

July 27, 2020

Primary Completion Date

August 25, 2025

Study Completion Date

August 25, 2025

Conditions
Melanoma
Interventions
DRUG

INCAGN02385

INCAGN02385 administered intravenously

DRUG

INCAGN02390

INCAGN02390 administered intravenously

DRUG

INCMGA00012.

INCMGA00012 administered intravenously

Trial Locations (17)

10016

Nyu Langone Laura and Isaac Perlmutter Cancer Center, New York

15232

Hillman Cancer Center, Pittsburgh

17033

Penn State Hershey Cancer Institute, Hershey

20817

Cancer Center For Blood Disorders A Division of American Oncology Partners P.A, Bethesda

28078

Carolina Bio Oncology, Huntersville

33136

University of Miami Sylvester Comprehensive Cancer Center, Miami

33612

H Lee Moffitt Cancer Center and Research, Tampa

52242

University of Iowa, Iowa City

63110

Washington University, St Louis

90025

The Angeles Clinic and Research Institute, Los Angeles

98109

University of Washington-Seattle Cancer Care Alliance, Seattle

07601

John Theurer Cancer Center, Hackensack University Medical Center, Hackensack

02060

Melanoma Institute Australia, Wollstonecraft

Unknown

Greenslopes Private Hospital, Brisbane

05042

Flinders Medical Centre, Bedford Park

03128

Box Hill Hospital, Box Hill

06009

One Clinical Research, Nedlands

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Incyte Corporation

INDUSTRY

NCT04370704 - Study of Combination Therapy With INCMGA00012 (Anti-PD-1), INCAGN02385 (Anti-LAG-3), and INCAGN02390 (Anti-TIM-3) in Participants With Select Advanced Malignancies | Biotech Hunter | Biotech Hunter