1,419
Participants
Start Date
May 25, 2020
Primary Completion Date
June 1, 2022
Study Completion Date
June 1, 2022
SARS-CoV-2 rS - Phase 1
Alternating intramuscular (deltoid) injections of SARS-CoV-2 rS (0.6 mL) on Days 0 and 21.
SARS-CoV-2 rS/Matrix-M Adjuvant - Phase 1
Alternating intramuscular (deltoid) injections of SARS-CoV-2 rS mixed with Matrix-M adjuvant (0.6 mL) on Days 0 and 21.
Normal saline solution (NSS), Placebo - Phase 1
Alternating intramuscular (deltoid) injections of placebo (0.6 mL) on Days 0 and 21.
Normal saline solution (NSS), Placebo - Phase 2
Intramuscular (deltoid) injections of placebo (0.5 mL).
SARS-CoV-2 rS/Matrix-M Adjuvant, Day 0 - Phase 1
Intramuscular (deltoid) injection of SARS-CoV-2 rS mixed with Matrix-M adjuvant (0.6 mL) on Day 0.
Normal saline solution (NSS), Placebo, Day 21 - Phase 1
Intramuscular injection of placebo (0.6 mL) in alternate deltoid on Day 21.
SARS-CoV-2 rS/Matrix-M Adjuvant - Phase 2
Intramuscular (deltoid) injections of SARS-CoV-2 rS co-formulated with Matrix-M adjuvant (0.5 mL).
Scientia Clinical Research Limited - Phase 2, Randwick
Australian Clinical Research Network - Phase 2, Maroubra
Paratus Clinical Research - Western Sydney - Phase 2, Blacktown
Paratus Clinical Research - Central Coast - Phase 2, Kanwal
Paratus Clinical Research - Canberra - Phase 2, Bruce
Center for Clinical Studies - Phase 1 and Phase 2, Melbourne
Barwon Health - Phase 2, Geelong
Q Pharm Pty Limited - Phase 1, Herston
University of the Sunshine Coast, Health Hub Morayfield - Phase 2, Morayfield
University of the Sunshine Coast - Phase 2, Sippy Downs
Meridian Clinical Research-(Rockville Maryland) - Platinum - PPDS - Phase 2, Rockville
Meridian Clinical Research-(Savannah Georgia) - Platinum - PPDS - Phase 2, Savannah
Central Kentucky Research Associates Inc - Phase 2, Lexington
Rapid Medical Research Inc - ERN-PPDS - Phase 2, Cleveland
Synexus Clinical Research US, Inc. - Cincinnati - Phase 2, Cincinnati
Alliance for Multispecialty Research, LLC - Phase 2, Newton
Alliance for Multispecialty Research, LLC - Phase 2, Wichita
Advanced Clinical Research - Meridian - ERN-PPDS - Phase 2, Meridian
Lead Sponsor
Coalition for Epidemic Preparedness Innovations
OTHER
Novavax
INDUSTRY