NCT04349826View on ClinicalTrials.gov

The Azithromycin and Cefixime Treatment of Typhoid in South Asia Trial (ACT-South Asia Trial)

PHASE4RecruitingINTERVENTIONAL
Enrollment

2,150

Participants

Timeline

Start Date

May 23, 2021

Primary Completion Date

September 30, 2025

Study Completion Date

September 30, 2025

Conditions
Typhoid Fever
Interventions
DRUG

Azithromycin

Azithromycin 20 mg/kg/day for 7 days

DRUG

Cefixime

cefixime 20-30 mg/kg/day for 7 days

DRUG

Placebo

cefixime-matched placebo for 7 days

Trial Locations (1)

Unknown

RECRUITING

Patan Hospital, Lalitpur

Sponsors

Collaborators (1)

Medical Research Council
All Listed Sponsors
collaborator

University of Oxford

OTHER

collaborator

Medical Research Council

OTHER_GOV

collaborator

Department for International Development, United Kingdom

OTHER_GOV

collaborator

Wellcome Trust

OTHER

lead

Oxford University Clinical Research Unit, Vietnam

OTHER