Cardiovascular Risk Reduction in Atrial Fibrillation Trial

NARecruitingINTERVENTIONAL
Enrollment

1,675

Participants

Timeline

Start Date

August 31, 2020

Primary Completion Date

June 30, 2024

Study Completion Date

December 31, 2025

Conditions
Atrial FibrillationHypertension
Interventions
DRUG

Intensive BP Control

Participants in the Intensive group have a goal of home SBP \<120 mm Hg. The CRAFT BP treatment protocol is flexible in terms of the choice and doses of antihypertensive medications, but there should be preferences among the drug classes, based on CVD outcome trials results and current guidelines. Use of once-daily antihypertensive agents will be encouraged unless alternative frequency is indicated/necessary. Combination of different classes of agents are encouraged to achieve the home SBP goal. Medications will not be provided by the CRAFT study.

DRUG

Standard BP Control

Participants in the Standard group has a goal of home SBP \<135 mmHg. The same principle of BP treatment in the Intensive BP arm will be used for the Standard BP arm. Medications will not be provided by the CRAFT study.

Trial Locations (1)

Unknown

RECRUITING

Beijing Anzhen Hospital, Beijing

Sponsors
All Listed Sponsors
collaborator

Heart Health Research Center

OTHER

collaborator

The George Institute for Global Health, China

OTHER

collaborator

The George Institute for Global Health, Australia

OTHER

collaborator

Fukuoka University

OTHER

lead

Beijing Anzhen Hospital

OTHER