A Clinical Trial to Study the Effectiveness of a Care Bundle to Prevent Bleeding After a Woman Has Given Birth

NACompletedINTERVENTIONAL
Enrollment

99,659

Participants

Timeline

Start Date

October 13, 2020

Primary Completion Date

March 24, 2023

Study Completion Date

March 24, 2023

Conditions
Post-Partum Haemorrhage
Interventions
BEHAVIORAL

E-MOTIVE intervention

"The E-MOTIVE intervention consists of three elements: 1) a strategy for early detection of PPH, which allows triggering of the 'first response' treatment bundle; 2) a 'first response' bundle called MOTIVE, based on the WHO guideline recommendations and consisting of uterine Massage, Oxytocic drugs, Tranexamic acid, IV fluids and Examination \& Escalation; and 3) an implementation strategy, focusing on simulation-based training with peer-assisted learning, local E-MOTIVE champions, feedback of actionable data to providers, calibrated drape with trigger line, and MOTIVE emergency trolley and/or carry case."

BEHAVIORAL

Usual care

Health facilities will continue to follow usual care as per the baseline period for the remainder of the intervention phase.

Trial Locations (6)

Unknown

University of Nairobi, Nairobi

Bayero University, Kano

Aga Khan University, Karachi

University of Cape Town, Cape Town

University of the Witwatersrand, Johannesburg

Muhimbili University of Health and Allied Sciences, Dar es Salaam

Sponsors
All Listed Sponsors
collaborator

University College, London

OTHER

collaborator

University of Melbourne

OTHER

collaborator

University of California

OTHER

collaborator

World Health Organization

OTHER

collaborator

King's College London

OTHER

collaborator

University of Liverpool

OTHER

collaborator

Jhpiego

OTHER

collaborator

Concept Foundation

OTHER

collaborator

University of Nairobi

OTHER

collaborator

University of Cape Town

OTHER

collaborator

Bayero University Kano, Nigeria

OTHER

collaborator

Muhimbili University of Health and Allied Sciences

OTHER

collaborator

University of Witwatersrand, South Africa

OTHER

collaborator

Ammalife

INDUSTRY

collaborator

Aga Khan University

OTHER

lead

University of Birmingham

OTHER