NCT04338191View on ClinicalTrials.gov

mFOLFOXIRI Versus mFOLFOX6 as Adjuvant Chemotherapy for Locally Advanced Colorectal Cancer

PHASE3RecruitingINTERVENTIONAL
Enrollment

638

Participants

Timeline

Start Date

April 1, 2020

Primary Completion Date

February 1, 2025

Study Completion Date

February 1, 2025

Conditions
Colorectal Cancer
Interventions
DRUG

mFOLFOXIRI adjuvant chemotherapy

mFOLFOXIRI (oxaliplatin 85 mg/m2, irinotecan 150 mg/m2, and folinic acid 400 mg/m2 followed by 5-fluorouracil 2400mg/m2 as a 46-hour continuous infusion on day 1) for 6 cycles

DRUG

mFOLFOX6 adjuvant chemotherapy

mFOLFOXIRI (oxaliplatin 85 mg/m2, and folinic acid 400 mg/m2 followed by 5-fluorouracil 400mg/m2 infusion, and 2400mg/m2 as a 46-hour continuous infusion on day 1) for 6 cycles

Trial Locations (1)

510655

RECRUITING

Gastrointestinal Hospital, Sun Yat-sen University, Guangzhou

All Listed Sponsors
lead

Sun Yat-sen University

OTHER