NCT04337879 - A Study of AL2846 Capsule Combined With Standard Chemotherapy Regimen in Subjects With Advanced Colorectal Cancer | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

July 20, 2020

Primary Completion Date

December 31, 2020

Study Completion Date

December 31, 2020

Conditions

Advanced Colorectal Cancer

Interventions

DRUG

AL2846

AL2846 is a multi-target receptor tyrosine kinase inhibitor, which has obvious selectivity for c-met.

DRUG

Calcium folate

Calcium folate 400mg/ ㎡ IV on day 1,15 in 28-day cycle

DRUG

5-FU

5-FU 2800mg/ ㎡ IV on day 1, 2, 15, 16 days in 28-day cycle.

DRUG

Oxaliplatin

Oxaliplatin 85mg/ ㎡ administered intravenously (IV) on day 1, day 15 in 28-day cycle.

DRUG

Irinotecan

Irinotecan 180mg/㎡ administered intravenously (IV) on day 1,15 in 28-day cycle.

Trial Locations (1)

RECRUITING

The First Hospital of China Medical University, Shengyang