Single Dose Azithromycin to Prevent Cholera in Children

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

920

Participants

Timeline

Start Date

October 31, 2021

Primary Completion Date

May 31, 2025

Study Completion Date

May 31, 2026

Conditions
Cholera
Interventions
DRUG

Azithromycin

Enrolled children in the intervention arm of this study will receive a single weight-based dose of azithromycin (20 mg/kg, to a maximum dose of 1 gram) administered by a trained study nurse within 12 hours of a member of their household testing positive for cholera.

BIOLOGICAL

Placebo

Enrolled children in the placebo arm of this study will receive a single dose of non-antibiotic placebo administered by a trained study nurse within 12 hours of a member of their household testing positive for cholera.

Trial Locations (1)

Unknown

icddr,b Dhaka hospital, Dhaka

All Listed Sponsors
collaborator

International Centre for Diarrhoeal Disease Research, Bangladesh

OTHER

lead

Massachusetts General Hospital

OTHER