The Broken Heart Study II (BHS-II)

NAActive, not recruitingINTERVENTIONAL
Enrollment

66

Participants

Timeline

Start Date

September 2, 2020

Primary Completion Date

February 28, 2025

Study Completion Date

February 28, 2026

Conditions
Takotsubo Cardiomyopathy
Interventions
OTHER

Stress reactivity test

"The protocol consists of Resting Baseline (BL), Emotion Recall (ER), followed by a Recovery Phase (RP). Heart rate and blood pressure are measured at baseline and then every 5 minutes during ER and RP.~Resting Baseline (BL - 10 min). The participant is instructed to rest quietly.~Emotion Recall (ER - 5-10 min). The participant is instructed to think about the incident associated with the onset of their cardiac event and bring to mind details of the incident. When the participants have the incident clearly in mind, they are instructed to relate the incident and their experience out loud; frequent questions to re-elicit the emotion are asked.~Recovery Phase (RP - 20 min). Upon completion of RP, the catheter is removed and participants are de-instrumented. Blood samples for plasma catecholamines, assessments of heart rate variability, and echocardiograms are performed 10-min into BL, 10-min into ER, and 18 minutes into RP."

Trial Locations (1)

02906

The Miriam Hospital, Providence

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

The Miriam Hospital

OTHER