Comparative Effectiveness of CET vs. SST in SMI (Serious Mental Illness)

NARecruitingINTERVENTIONAL
Enrollment

378

Participants

Timeline

Start Date

June 1, 2021

Primary Completion Date

January 31, 2026

Study Completion Date

January 31, 2026

Conditions
Schizophrenia and Related Disorders
Interventions
BEHAVIORAL

Cognitive Enhancement Therapy

CET's group-based exercises are delivered for 1.5 hours each week in a group of 6-8 participants led by a clinician and an assistant, for one year. During each of three modules (basic concepts, social cognition, CET applications), the groups focus on acquisition of adult social milestones in perspective-taking, social context appraisal, and other aspects of social cognition, with psychoeducational lectures, homework assignments, and in-group exercises. Weekly supervision sessions for the clinician trainers will include review of how patients respond to the different demands of computer-based training and group-based exercises and guidance about improving engagement in both.

BEHAVIORAL

Social Skills Training

"The psychosocial component involves weekly skills training classes delivered over one year, with modules including Communicating Effectively, Making and Keeping Friends, Making the Most of Leisure Time, Healthy Living, Using Medications Effectively, and Making the Most of a Health Care Visit (Pratt et al., 2008). Participants attend two sessions each week (normally morning and afternoon of the same day): a 90-minute session focused on a specific skill and a 60-minute session in which the specific skill is used in role-play exercises."

Trial Locations (5)

06106

RECRUITING

Hartford Hospital - Institute of Living, Hartford

04102

RECRUITING

Maine Medical Center, Portland

02115

RECRUITING

Massachusetts Mental Health Center, Boston

02215

ACTIVE_NOT_RECRUITING

Beth Israel Deaconess Medical Center, Boston

01603

RECRUITING

UMass Medical School, Worcester

All Listed Sponsors
collaborator

Patient-Centered Outcomes Research Institute

OTHER

lead

Beth Israel Deaconess Medical Center

OTHER