A Trial of SHR-1316/Placebo in Combination With Chemotherapy in Patients With Resectable NSCLC

PHASE3RecruitingINTERVENTIONAL
Enrollment

537

Participants

Timeline

Start Date

July 14, 2020

Primary Completion Date

April 15, 2023

Study Completion Date

December 15, 2026

Conditions
Non-Small-Cell Lung Cancer
Interventions
DRUG

SHR-1316、Paclitaxel (Albumin Bound)、Carboplatin

Drug: SHR-1316, an engineered anti-PD-L1 antibody will be administered as intravenous (IV) infusion on Day 1 of each 21-day cycle Drug: Paclitaxel (Albumin Bound) will be administered intravenously on Day 1,8,15 of each 21-day cycle Drug: Carboplatin will be administered intravenously on Day 1 of each 21-day cycle

DRUG

SHR-1316、Chemotherapeutic

Drug: SHR-1316, an engineered anti-PD-L1 antibody will be administered as intravenous (IV) infusion on Day 1 of each 21-day cycle Drug: Chemotherapeutic drugs will be administered on Day 1 of each 21day cycle, if applicable, they will also be administered on Day 8 and/or Day 15 according to the drug package insert

DRUG

Placebo、Chemotherapeutic

Drug: Placebo, will be administered as intravenous (IV) infusion on Day 1 of each 21-day cycle Drug: Chemotherapeutic drugs will be administered on Day 1 of each 21day cycle, if applicable, they will also be administered on Day 8 and/or Day 15 according to the drug package insert

Trial Locations (7)

100000

RECRUITING

Beijing Cancer Hospital, Beijing

200032

RECRUITING

Zhongshan Hospital, Fudan University, Shanghai

210009

RECRUITING

JiangSu Cancer Hospital, Nanjing

310022

RECRUITING

ZheJiang Cancer Hospital, Hangzhou

450000

RECRUITING

Henan Cancer Hospital, Zhengzhou

510000

RECRUITING

Guangdong Provincial People's Hospital, Guangzhou

610041

RECRUITING

West China Hospital,Sichuan University, Chengdu

All Listed Sponsors
lead

Jiangsu HengRui Medicine Co., Ltd.

INDUSTRY