TRAnexamic Acid for Preventing Blood Loss Following a Cesarean Delivery in Women With Placenta pREVIA

PHASE3RecruitingINTERVENTIONAL
Enrollment

1,380

Participants

Timeline

Start Date

August 7, 2020

Primary Completion Date

June 30, 2027

Study Completion Date

September 30, 2027

Conditions
Postpartum Hemorrhage
Interventions
DRUG

Tranexamic Acid / Sodium chloride

After the routine prophylactic IV or IM injection of the uterotonic used in the hospital protocol's -either oxytocin or carbetocin - (as recommended by the 2014 guidelines for prevention and management of postpartum hemorrhage from the CNGOF), the intervention will be the IV administration of a 10-ml blinded ampoule of the study drug (either TXA or placebo according to the randomisation sequence) to the patient within 3 minutes after birth, slowly (over 30-60 seconds), once the cord has been clamped

Trial Locations (1)

Unknown

RECRUITING

CHU Bordeaux, Bordeaux

All Listed Sponsors
lead

University Hospital, Bordeaux

OTHER