A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single-Ascending and Multiple Doses of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Healthy Japanese Participants

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

April 23, 2020

Primary Completion Date

September 10, 2020

Study Completion Date

September 10, 2020

Conditions

Healthy Participants

Interventions

DRUG

Eplontersen

Eplontersen administered SC

DRUG

Placebo

Eplontersen-matching placebo administered SC

Trial Locations (1)

WCCT Global, Cypress