Prematurity Risk Assessment Combined With Clinical Interventions for Improving Neonatal outcoMEs

NAActive, not recruitingINTERVENTIONAL
Enrollment

6,500

Participants

Timeline

Start Date

November 6, 2020

Primary Completion Date

December 6, 2024

Study Completion Date

December 30, 2026

Conditions
Preterm LaborPreterm Birth
Interventions
OTHER

Multimodal intervention strategy

"* Once weekly nurse support~* 200 mg/daily micronized progesterone as vaginal suppository~* 81 mg/daily low dose aspirin~* two transvaginal ultrasounds~* cerclage placement if cervical length is less than or equal to 10 mm prior to 24 weeks gestation"

Trial Locations (18)

10029

Mt Sinai, New York

19713

Delaware/Christiana Care, Newark

19801

Emerald Coast, Panama City

22042

Inova Health Care Services, Falls Church

22908

University of Virginia, Charlottesville

23235

VPFW, Richmond

40536

University of Kentucky Healthcare, Lexington

43214

Ohio Health, Columbus

44195

Cleveland Clinic, Cleveland

48073

Beaumont Hospital, Royal Oak

53226

MCW, Milwaukee

70115

Ochsner, New Orleans

71101

LSU, Shreveport

89106

High Risk Pregnancy Center, Las Vegas

92121

UCSD, San Diego

06519

Yale, New Haven

02118

Boston Medical Center, Boston

77555-0587

UTMB, Galveston

All Listed Sponsors
collaborator

High Risk Pregnancy Center, Las Vegas, Nevada

OTHER

lead

Sera Prognostics, Inc.

INDUSTRY