NCT04294160 - A Study of Select Drug Combinations in Adult Patients With Advanced/Metastatic BRAF V600 Colorectal Cancer | Biotech Hunter

Enrollment

122

Participants

Timeline

Start Date

July 22, 2020

Primary Completion Date

September 25, 2024

Study Completion Date

September 25, 2024

Conditions

BRAF V600 Colorectal Cancer

Interventions

DRUG

Dabrafenib

Capsule for oral use

DRUG

LTT462

Capsule for oral use

DRUG

Trametinib

Tablet for oral use

DRUG

LXH254

Tablet for oral use

DRUG

TNO155

Capsule for oral use

BIOLOGICAL

Spartalizumab

Liquid in vial (Concentrate for solution for infusion) for intravenous use

BIOLOGICAL

Tislelizumab

Liquid in vial (Concentrate for solution for infusion) for intravenous use

Trial Locations (18)

1000

Novartis Investigative Site, Brussels

2145

Novartis Investigative Site, Westmead

3000

Novartis Investigative Site, Leuven

28009

Novartis Investigative Site, Madrid

37203

Sarah Cannon Research Institute SC, Nashville

45147

Novartis Investigative Site, Essen

46010

Novartis Investigative Site, Valencia

77030

Uni Of TX MD Anderson Cancer Cntr, Houston

89081

Novartis Investigative Site, Ulm

90095

University of California LA Santa Monica Location, Los Angeles

119228

Novartis Investigative Site, Singapore

6423906

Novartis Investigative Site, Tel Aviv

02114

Massachusetts General Hospital Massachusetts General Hospital, Boston

M5G 2M9

Novartis Investigative Site, Toronto

01307

Novartis Investigative Site, Dresden

NL-2722 EP

Novartis Investigative Site, Zoetermeer

08035

Novartis Investigative Site, Barcelona

M20 2BX

Novartis Investigative Site, Manchester