Long-Term Analysis of DImethyl Fumarate, to Slow the Growth of Areas of Geographic Atrophy

PHASE2RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

February 7, 2022

Primary Completion Date

October 7, 2025

Study Completion Date

October 7, 2027

Conditions
Age-related Macular Degeneration (AMD)
Interventions
DRUG

Dimethyl Fumarate (TECFIDERA™)

Dimethyl fumarate is a white to off-white powder that is highly soluble in water with a molecular mass of 144.13, containing 120 mg or 240 mg of dimethyl fumarate The starting dose for TECFIDERA is 120 mg twice a day orally. After 7 days, the dose should be increased to the maintenance dose of 240 mg twice a day orally. Body weight, gender, and age do not require dosage adjustment.

OTHER

No active : no treatment

30 patients will receive no specific treatment (standard of care) up to 24 months following randomization.

Trial Locations (1)

94000

RECRUITING

Centre intercommunal de Créteil, Créteil

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER