60
Participants
Start Date
February 7, 2022
Primary Completion Date
October 7, 2025
Study Completion Date
October 7, 2027
Dimethyl Fumarate (TECFIDERA™)
Dimethyl fumarate is a white to off-white powder that is highly soluble in water with a molecular mass of 144.13, containing 120 mg or 240 mg of dimethyl fumarate The starting dose for TECFIDERA is 120 mg twice a day orally. After 7 days, the dose should be increased to the maintenance dose of 240 mg twice a day orally. Body weight, gender, and age do not require dosage adjustment.
No active : no treatment
30 patients will receive no specific treatment (standard of care) up to 24 months following randomization.
RECRUITING
Centre intercommunal de Créteil, Créteil
Assistance Publique - Hôpitaux de Paris
OTHER