2,400
Participants
Start Date
December 1, 2019
Primary Completion Date
July 31, 2028
Study Completion Date
March 31, 2029
Dexmedetomidine Hydrochloride Group
Dexmedetomidine will be initiated prior to transfer to the CVICU with loading dose of 1.2 ug/kg over approximately 20-60 minutes. This will be followed by an infusion at 0.3 ug/kg/h in CVICU for up to 12 hours from the time DEX infusion started or until the patient is ready for discharge from the CVICU (whichever is earlier). Any additional sedatives necessary at the discretion of ICU.
RECRUITING
Royal Columbian Hospital, Vancouver
RECRUITING
St. Paul's Hospital, Vancouver
RECRUITING
London Health Sciences, London
RECRUITING
Sunnybrook Health Sciences Centre, Toronto
RECRUITING
Toronto General Hospital, Toronto
RECRUITING
University of Saskatchewan, Saskatoon
Collaborators (2)
London Health Sciences Centre
OTHER
University Health Network, Toronto
OTHER
McMaster University
OTHER
Canadian Institutes of Health Research (CIHR)
OTHER_GOV
The Dana Foundation
OTHER
Brain Canada
OTHER
Alzheimer's Association
OTHER
Hamilton Health Sciences Corporation
OTHER
University of Saskatchewan
OTHER
Fraser Health
OTHER
Providence Health & Services
OTHER
Sunnybrook Health Sciences Centre
OTHER