Asian Diabetes Outcomes Prevention Trial

PHASE4RecruitingINTERVENTIONAL
Enrollment

2,400

Participants

Timeline

Start Date

July 1, 2019

Primary Completion Date

June 30, 2022

Study Completion Date

June 30, 2034

Conditions
Diabetes MellitusCardiovascular Diseases
Interventions
DRUG

Renin-angiotensin-aldosterone system inhibitors

Research participants in the intensive therapy arm should be strongly encouraged to follow the intensive treatment strategy. Every attempt should be made to up-titrate RAS-antagonists and beta-blockers (max dosage, unless contraindicated) as well as preferentially use SGLT2i (standard dosage, as required) throughout the trial.

DRUG

Beta blocker

Research participants in the intensive therapy arm should be strongly encouraged to follow the intensive treatment strategy. Every attempt should be made to up-titrate RAS-antagonists and beta-blockers (max dosage, unless contraindicated) as well as preferentially use SGLT2i (standard dosage, as required) throughout the trial.

DRUG

SGLT2 Inhibitor - Sodium Glucose Cotransporter Subtype 2 Inhibitor Product

Research participants in the intensive therapy arm should be strongly encouraged to follow the intensive treatment strategy. Every attempt should be made to up-titrate RAS-antagonists and beta-blockers (max dosage, unless contraindicated) as well as preferentially use SGLT2i (standard dosage, as required) throughout the trial.

Trial Locations (1)

169608

RECRUITING

Singapore General Hospital (SGH), Singapore

All Listed Sponsors
collaborator

Singapore General Hospital

OTHER

collaborator

Mackay Memorial Hospital

OTHER

collaborator

National Taiwan University Hospital

OTHER

collaborator

Peking University People's Hospital

OTHER

collaborator

Medanta, The Medicity, India

OTHER

collaborator

Public Health Foundation of India

OTHER

collaborator

Putrajaya Hospital, Malaysia

UNKNOWN

collaborator

Universiti Teknologi Mara

OTHER

lead

National Heart Centre Singapore

OTHER