Study of BGB-10188 as Monotherapy, and in Combination With Zanubrutinib, and Tislelizumab

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

97

Participants

Timeline

Start Date

May 25, 2020

Primary Completion Date

August 28, 2024

Study Completion Date

August 28, 2024

Conditions
Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaFollicular LymphomaMarginal Zone LymphomaMantle Cell LymphomaDiffuse Large B Cell LymphomaAdvanced Solid Tumor
Interventions
DRUG

BGB-10188

Administered as specified in the treatment arm

DRUG

Zanubrutinib

Administered as specified in the treatment arm

DRUG

Tislelizumab

Administered as specified in the treatment arm

Trial Locations (24)

2010

Saint Vincents Hospital Sydney, Darlinghurst

2148

Blacktown Cancer and Haematology Centre, Blacktown

3084

Austin Health, Heidelberg

3168

Monash Health, Clayton

4120

Gallipoli Medical Research Foundation, Greenslopes

4217

Pindara Private Hospital, Benowa

5000

Royal Adelaide Hospital, Adelaide

6005

Perth Blood Institute, West Perth

100142

Beijing Cancer Hospital, Beijing

130021

The First Hospital of Jilin University, Changchun

200000

Fudan University Shanghai Cancer Center, Shanghai

200032

Affiliated Zhongshan Hospital of Fudan University, Shanghai

215006

The First Affiliated Hospital of Soochow University, Suzhou

272000

Jining No Peoples Hospital West Branch, Jining

310009

Zhejiang University College of Medicine Second Affiliated Hospital, Hangzhou

325000

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou

350014

Fujian Cancer Hospital, Fuzhou

410013

The Third Xiangya Hospital of Central South University, Changsha

430022

Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan

430079

Hubei Cancer Hospital, Wuhan

450000

Henan Cancer Hospital, Zhengzhou

518036

Peking University Shenzhen Hospital, Shenzhen

610041

West China Hospital, Sichuan University, Chengdu

750004

General Hospital of Ningxia Medical University, Yinchuan

Sponsors

Lead Sponsor

All Listed Sponsors
lead

BeiGene

INDUSTRY