20
Participants
Start Date
April 13, 2020
Primary Completion Date
October 2, 2023
Study Completion Date
October 2, 2023
ATG-019
ATG-019 30 mg QoD×3 is selected as the staring dose. Oral ATG-019 will be taken three times a week every other day (Days 1, 3, 5, 8, 10, 12, 15, 17, 19, 22, 24, and 26) during each 28-day cycle.
ATG-019 + Niacin ER
ATG-019 60 mg is selected as starting dose. Oral ATG-019 will be taken three times a week every other day (Days 1, 3, 5, 8, 10, 12, 15, 17, 19, 22, 24, and 26) during each 28-day cycle. And a starting dose of 500 mg niacin ER (may be titrated up to 1,000 mg of daily dose, per label) co-administered with each dose of ATG-019.
Tri-Service General Hospital (TSGH), Taipei
Kaohsiung Medical University Chung-Ho Memorial Hospital (KMUH), Kaohsiung City
China Medical University Hospital (CMUH), Taichang
National Cheng Kung University Hospital (NCKUH), Tainan City
Kaohsiung Chang Gung Memorial Hospital (CGMHKS), Kaohsiung City
Fudan University Zhongshan Hospital, Shanghai
Xinhua Hospital Affiliated To Shanghai Jiaotong University School of Medicine, Shanghai
Jiangsu Province Hospital, Nanjing
Lead Sponsor
Antengene Therapeutics Limited
INDUSTRY