TBI Using IMRT (VMAT or Tomotherapy) for the Prevention of Pul Toxicities in Patients Undergoing Donor SCT

PHASE1Active, not recruitingINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

February 28, 2020

Primary Completion Date

July 14, 2026

Study Completion Date

July 14, 2026

Conditions

Acute LeukemiaMyelodysplastic Syndrome

Interventions

PROCEDURE

Hematopoietic Cell Transplantation

Undergo HCT

RADIATION

Intensity-Modulated Radiation Therapy

Undergo IMRT

RADIATION

Tomotherapy

Undergo IMRT with tomotherapy

RADIATION

Total-Body Irradiation

Undergo TBI

RADIATION

Volume Modulated Arc Therapy

Undergo IMRT with VMAT

Trial Locations (1)

City of Hope Medical Center, Duarte

All Listed Sponsors

collaborator

National Cancer Institute (NCI)

NIH

lead

City of Hope Medical Center

OTHER