400
Participants
Start Date
April 21, 2020
Primary Completion Date
December 2, 2023
Study Completion Date
March 2, 2028
Neoadjuvant immunochemotherapy
"Neo-adjuvant chemotherapy(cisplatin and paclitaxel):~Paclitaxel, 175mg/m2, d1, Cisplatin, 75mg/m2, d1, 3 week, 2 cycles. JS001, 240mg ivgtt, d3, \>30min, 3week, 2 cycles~Surgery:~2-3weeks after Neo-adjuvant chemotherapy Surgeons: the operation shall be performed by senior thoracic surgeons. Try to achieve the consistency of operation quality.~Operation: the thoracic esophagectomy must be through right thoracic cavity. (open and minimally invasive McKeown or Ivor Lewis). Total two-field lymphadenectomy (right and left recurrent laryngeal nerve lymph nodes must be included).~After surgery/ maintain period:~JS001, 240mg ivgtt, d3, \>30min, 3week (8 cycles at most)"
RECRUITING
Henan Cancer Hospital (The Affiliated Cancer Hospital of Zhengzhou University), Zhengzhou
Henan Cancer Hospital
OTHER_GOV