Study to Evaluate the Safety of CB-280 in Patients With Cystic Fibrosis

PHASE1CompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

July 3, 2020

Primary Completion Date

November 23, 2021

Study Completion Date

November 23, 2021

Conditions
Cystic Fibrosis
Interventions
DRUG

CB-280

CB-280, oral capsule administered twice daily at the assigned dose level for 14 days

DRUG

Placebos

Placebo oral capsule administrated twice daily at the assigned dose level for 14 days

Trial Locations (20)

10532

New York Medical College at Westchester Medical Center, Hawthorne

17033

Hershey Medical Center Pennsylvania State University, Hershey

21287

Johns Hopkins University, Baltimore

23219

Virginia Commonwealth University, Richmond

27514

UNC Marsico Clinical Research Center, Chapel Hill

29425

Medical University of South Carolina, Charleston

32610

University of Florida, Gainesville

44106

University Hospitals Cleveland Medical Center, Cleveland

46202

Indiana University, Indianapolis

59101

Billings Clinic, Billings

60025

The Cystic Fibrosis Institute, Glenview

66160

University of Kansas Medical Center, Kansas City

72205

University of Arkansas for Medical Sciences, Little Rock

84132

University of Utah, Salt Lake City

90806

Long Beach Memorial Medical Center, Long Beach

02115

Boston Children's Hospital, Brigham & Women's Hospital, Boston

05446

Vermont Lung Center at the University of Vermont Medical Center, Colchester

T2N 4N1

University of Calgary, Calgary

V6Z1Y6

St. Pauls' Hospital, Vancouver

H4A 3J1

McGill University Health Center, Montreal

Sponsors
All Listed Sponsors
lead

Calithera Biosciences, Inc

INDUSTRY

NCT04279769 - Study to Evaluate the Safety of CB-280 in Patients With Cystic Fibrosis | Biotech Hunter | Biotech Hunter