Ovarian Function Following Intraovarian Injection of PRP

NARecruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

February 24, 2020

Primary Completion Date

December 31, 2025

Study Completion Date

June 30, 2026

Conditions
Diminished Ovarian ReserveDiminished Ovarian Reserve Due to Advanced Maternal Age
Interventions
PROCEDURE

PRP - Platelet Rich Plasma

Using a sterile vacutainer technique two 8 ml samples of whole blood is drawn into two Regen Lab A-PRP vacutainers with gel separator and citrate. Invert the tube to mix with citrate. The whole blood undergoes two centrifugations, once for 3 minutes and again for 5 minutes. Using a 20-gauge 6-inch spinal needle 2 ml of Platelet POOR Plasma will be drawn off the supernatant from each tube to leave 2.5 ml of Platelet Rich Plasma in the tube. The tube is inverted several times to suspend the platelet pellet. The prepared plasma labeled with the participants name and randomization code will be transported to the procedure room.

PROCEDURE

PPP - Platelet Poor Plasma

Using a sterile vacutainer technique two 8 ml samples of whole blood is drawn into two Regen Lab A-PRP vacutainers with gel separator and citrate. Invert the tube to mix with citrate. The whole blood undergoes two centrifugations, once for 3 minutes and again for 5 minutes. Using a 20-gauge 6-inch spinal needle 2 ml of Platelet POOR Plasma will be drawn off the supernatant from each tube. The prepared plasma will be transported to the procedure room. The prepared plasma labeled with the participants name and randomization code will be transported to the procedure room.

Trial Locations (1)

10021

RECRUITING

Center for Human Reproduction, New York

All Listed Sponsors
lead

Center for Human Reproduction

OTHER