A Study to Evaluate the Safety and Tolerability of Venetoclax Tablets in Combination With Capecitabine Tablets in Adult Participants With Hormone Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer Who Had Disease Progression During or After CDK4/6 Inhibitor Therapy

PHASE1TerminatedINTERVENTIONAL
Enrollment

4

Participants

Timeline

Start Date

May 21, 2020

Primary Completion Date

October 8, 2020

Study Completion Date

October 8, 2020

Conditions
Breast CancerCancer
Interventions
DRUG

Venetoclax

Tablet; Oral

DRUG

Capecitabine

Tablet; Oral

Trial Locations (18)

10117

Charite Universitaetsmedizin Berlin /ID# 215287, Berlin

29605

Greenville Health System Cance /ID# 216059, Greenville

55455

Masonic Cancer Center /ID# 216101, Minneapolis

60435

Joliet Oncology-Hematology Associates, LTD /ID# 215051, Joliet

69120

Universitaetsklinik Heidelberg /ID# 214679, Heidelberg

72076

Universitatsklinikum Tubingen /ID# 217021, Tübingen

77030

MD Anderson Cancer Center /ID# 214867, Houston

84106

Utah Cancer Specialists /ID# 215375, Salt Lake City

89081

Universitaetsklinikum Ulm /ID# 214678, Ulm

98104

Swedish Cancer Institute /ID# 216120, Seattle

02114

Massachusetts General Hospital /ID# 214833, Boston

02215

Dana-Farber Cancer Institute /ID# 214832, Boston

10065-6007

Memorial Sloan Kettering Cancer Center /ID# 214886, New York

19104-5502

University of Pennsylvania /ID# 216357, Philadelphia

37232-6307

Vanderbilt University Med Ctr /ID# 213852, Nashville

464-8681

Aichi Cancer Center Hospital /ID# 224527, Nagoya

00935

Pan American Center for Oncology Trials, LLC /ID# 216862, Rio Piedras

00917-3104

GCM Medical Group PSC - Hato Rey /ID# 216904, San Juan

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AbbVie

INDUSTRY