55
Participants
Start Date
February 12, 2020
Primary Completion Date
May 15, 2023
Study Completion Date
June 1, 2025
SBRT with additional treatment planning dose optimization
Lung SBRT 50-60Gy in 5 fractions with standard of care planning and additional treatment planning dose optimization criteria to minimize decrease in lymphocyte count beyond dosimetric criteria from RTOG 0915/0813 SBRT trials.
SBRT with standard of care planning only
Lung SBRT 50-60Gy in 5 fractions with standard of care planning (no additional dose optimization beyond SOC)
Blood Draws
CBC w/ Diff and additional blood analysis for all participants in both groups. Blood draws will prior to treatment, end of treatment, 4 weeks after treatment, and 6 months after treatment.
University of Virginia, Charlottesville
University of Virginia
OTHER